The Momen-Heravi Lab, headed by Fatemeh Momen-Heravi, is part of the College of Dental Medicine and the Herbert Irving Comprehensive Cancer Center at Columbia University Irving Medical Center.
We strive to perform innovative science to understand the biological mechanisms underlying carcinogenesis mediated by tumor immune cell interactions and exploit tumor vulnerabilities to cure cancer.
Extracellular Vesicles
Genome Engineering
Tumor Biomarker
Periodontal Disease
RESEARCH GOAL
Understanding the interplay between the tumor, exosomes/extracellular vesicles, and tumor microenvironment to identify actionable molecular targets for head and neck cancer.
Develop novel gene editing methods to edit tumor mutations and tumor-associated macrophages for treatment of head and neck cancer and lung cancer.
Examining the role of innate immunity in the pathogenesis of periodontal disease and its convergence with diabetes and carcinogenesis.